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Drugs in development · updated 30 October 2026

Lamivudine: clinical trials and development status

Other names and codes: Epivir-Hbv, Zeffix

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 8 August 1996

As of 30 October 2026 Lamivudine is in 18 active clinical trials (recruiting or ongoing, phases I–III) for 9 diseases. The most advanced phase is III.

18Active trials
IIIMost advanced phase
9Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Lamivudine and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
HIV infectionIII5NCT05979311
Acquired Immunodeficiency SyndromeIII3NCT05979311
Hepatitis BIII1NCT04704024
TuberculosisIII1NCT06497465
Cognitive dysfunctionII1NCT06519357
Rett syndromeII1NCT07640503
Systemic lupus erythematosusII1NCT06356740
GliomaI1NCT06428045
Smoking cessationI1NCT07058974

Everything on Lamivudine

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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