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Drugs in development · updated 30 October 2026

Lisaftoclax: clinical trials and development status

Other names and codes: APG-2575

NLM verified identityNot approved in the USNo EMA authorisationEstimated launch Feb 2028 – Dec 2028 (Phuturdex estimate)

As of 30 October 2026 Lisaftoclax is in 28 active clinical trials (recruiting or ongoing, phases I–III) for 14 diseases. The most advanced phase is III.

28Active trials
IIIMost advanced phase
14Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Lisaftoclax and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Acute myeloid leukemiaIII7NCT07686965
Acute promyelocytic leukemiaII–III1NCT07597941
Chronic lymphocytic leukemiaII3NCT05147467
Diffuse large B-cell lymphomaI–II2NCT07601607
Mantle cell lymphomaII2NCT07272499
Non-Hodgkin lymphomaII2NCT04496349
Interdigitating dendritic cell sarcomaII1NCT07255963
Lymphoma, Primary Cutaneous Anaplastic Large CellII1NCT07717580
Mycosis fungoidesII1NCT07717580
NeuroblastomaI–II1NCT05701306
Residual neoplasmII1NCT07813390
T-cell prolymphocytic leukemiaII1NCT04496349
LeukemiaI1NCT05495035
Precursor lymphoblastic lymphoma/leukemiaI1NCT05495035

Everything on Lisaftoclax

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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