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Drugs in development · updated 30 October 2026

Midodrine: clinical trials and development status

Other names and codes: Proamatine

NLM verified identityApproved in the US (FDA)

As of 30 October 2026 Midodrine is in 3 active clinical trials (recruiting or ongoing, phases I–III) for 7 diseases. The most advanced phase is II–III.

3Active trials
II–IIIMost advanced phase
7Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Midodrine and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
HypotensionII–III2NCT06405555
Heart failureII–III1NCT06405555
Left ventricular dysfunctionII–III1NCT06405555
Postural orthostatic tachycardia syndromeI–II1NCT00262470
SepsisII1NCT06319248
Sinus tachycardiaI–II1NCT00262470
TachycardiaI–II1NCT00262470

Everything on Midodrine

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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