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Drugs in development · updated 30 October 2026

Neratinib: clinical trials and development status

Other names and codes: Nerlynx

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 31 August 2018

As of 30 October 2026 Neratinib is in 24 active clinical trials (recruiting or ongoing, phases I–III) for 24 diseases. The most advanced phase is III.

24Active trials
IIIMost advanced phase
24Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Neratinib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Breast neoplasmIII8NCT05760612
Biliary tract neoplasmIII1NCT05615818
MetastasisII3NCT05564377
Brain NeoplasmsII2NCT04965064
Ovarian neoplasmII2NCT05564377
Stomach neoplasmII2NCT06109467
Triple-negative breast neoplasmII2NCT01042379
Breast lobular carcinomaII1NCT05919108
CarcinomaII1NCT06813079
Central nervous system neoplasmI–II1NCT02932280
Endometrial neoplasmII1NCT05564377
EpendymomaII1NCT04374305
Fallopian tube neoplasmII1NCT05564377
GlioblastomaII1NCT02977780
HemangiosarcomaII1NCT01042379
LeukemiaI–II1NCT02932280
LymphomaI–II1NCT02932280
MeningiomaII1NCT04374305
NeoplasmII1NCT01042379
Neurofibromatosis 2II1NCT04374305
Neuroma, AcousticII1NCT04374305
Pancreatic ductal carcinomaII1NCT06813079
Gastrointestinal neoplasmI1NCT05274048
Pancreatic neoplasmI1NCT05372614

Everything on Neratinib

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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