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Drugs in development · updated 30 October 2026

OnabotulinumtoxinA: clinical trials and development status

Other names and codes: Botox, Botox Cosmetic

NLM verified identityApproved in the US (FDA)

As of 30 October 2026 OnabotulinumtoxinA is in 17 active clinical trials (recruiting or ongoing, phases I–III) for 10 diseases. The most advanced phase is III.

17Active trials
IIIMost advanced phase
10Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow OnabotulinumtoxinA and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Overactive bladderII–III2NCT05878951
Urinary incontinenceII–III2NCT05878951
MigraineIII1NCT07040813
OsteoarthritisII–III1NCT06902805
Premature ejaculationII–III1NCT06851598
Raynaud diseaseIII1NCT05698979
Thromboangiitis obliteransIII1NCT05698979
Urologic DiseasesII–III1NCT05878951
Head and neck neoplasmsII1NCT06530524
Prostatic NeoplasmsI–II1NCT07796490

Everything on OnabotulinumtoxinA

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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