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Drugs in development · updated 9 November 2026

UMEC: clinical trials and development status

Other names and codes: GSK573719, Incruse Ellipta, Rolufta Ellipta (previously Rolufta), Incruse Ellipta (previously Incruse)

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 28 April 2014

As of 9 November 2026 UMEC is in 4 active clinical trials (recruiting or ongoing, phases I–III) for 3 diseases. The most advanced phase is III.

4Active trials
IIIMost advanced phase
3Diseases studied

Summary updated every week · data as of 9 November 2026. In Phuturdex you can follow UMEC and get an email at every change or safety alert.

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What it is

The bromide salt form of umeclidinium, a muscarinic receptor antagonist, with bronchodilator activity. Although it does not display selectivity for specific muscarinic receptors, on topical application, umeclidinium acts mainly on M3 muscarinic receptors located on smooth muscle cells, thereby preventing smooth muscle contraction and resulting in bronchodilatory effect.

Source: NCI Thesaurus

Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
AsthmaIII3NCT05757102
Chronic obstructive pulmonary diseaseIII1NCT04536675
Non-small-cell lung carcinomaIII1NCT04536675

Everything on UMEC

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 9 November 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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