Phuturdex › Diseases › Cardiomegaly
Drugs in development · updated 30 October 2026
Cardiomegaly: drugs in development
As of 30 October 2026 there are 3 active clinical trials (recruiting or ongoing, phases I–III) on 3 drugs for cardiomegaly. 0 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| TrametinibMekinist®, Spexotras® | II | 1 | NCT06555237 |
| MetforminRiomet Er®, Glumetza® | I | 1 | NCT06424860 |
| PrednisonePredinisone, Cortancyl | I | 1 | NCT05302271 |
Sorted by most advanced phase and number of active trials.
All 3 drugs, with the details
In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.
Open in Phuturdex →Specific forms
- Dilated cardiomyopathy 7 drugs
- Left ventricular hypertrophy 4 drugs
- Cardiomyopathies 23 drugs
- Heart failure 104 drugs
- Heart disease 17 drugs
- Hypertrophic cardiomyopathy 16 drugs
- Arterial hypertension 119 drugs
- Inflammation 85 drugs
- Atherosclerosis 34 drugs
- Coronary artery disease 34 drugs
- Cardiovascular disease 71 drugs
- Friedreich ataxia 9 drugs
Broader categories
- Heart disease 17 drugs
- Cardiovascular disease 71 drugs
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities 4 drugs
- Brain Diseases 23 drugs
- Central nervous system disease 38 drugs
- Nervous System Diseases 39 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D006332 “Cardiomegaly”.