Phuturdex › Diseases › Polyneuropathies
Drugs in development · updated 30 October 2026
Polyneuropathies: drugs in development
As of 30 October 2026 there are 3 active clinical trials (recruiting or ongoing, phases I–III) on 3 drugs for polyneuropathies. One is experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Experimental drugs
Not yet approved by the US FDA for any indication.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| Nucresiran | III | 1 | NCT07223203 |
Sorted by most advanced phase and number of active trials.
Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| AcoramidisAttruby®, Beyonttra® | III | 2 | NCT07116473 |
| VutrisiranAmvuttra® | III | 1 | NCT07223203 |
Sorted by most advanced phase and number of active trials.
All 3 drugs, with the details
In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.
Open in Phuturdex →Specific forms
- Chronic inflammatory demyelinating polyradiculoneuropathy 23 drugs
- Myasthenia gravis 49 drugs
- Autoimmune disease of the nervous system 21 drugs
- Hereditary sensory and autonomic neuropathy 6 drugs
- Multiple sclerosis 93 drugs
- Neuromyelitis optica 25 drugs
- POEMS syndrome 5 drugs
- Guillain–Barré syndrome 3 drugs
- Charcot–Marie–Tooth disease 3 drugs
- Myositis 42 drugs
- Autoimmune disease 94 drugs
- Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease 9 drugs
Broader categories
- Nervous System Diseases 39 drugs
- Metabolic disease 30 drugs
- Nutritional and metabolic diseases 5 drugs
- Neuromuscular disease 14 drugs
- Proteostasis Deficiencies 7 drugs
- Peripheral Nervous System Diseases 16 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: NLM MeSH; NLM MeSH term: D011115 “Polyneuropathies”.