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Drugs in development · updated 30 October 2026

Vutrisiran: clinical trials and development status

Other names and codes: Amvuttra

FDA verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 15 September 2022

As of 30 October 2026 Vutrisiran is in 3 active clinical trials (recruiting or ongoing, phases I–III) for 5 diseases. The most advanced phase is III.

3Active trials
IIIMost advanced phase
5Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Vutrisiran and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
AmyloidosisIII3NCT06679946
Amyloidosis, Hereditary, Transthyretin-RelatedIII2NCT06679946
CardiomyopathiesIII2NCT06679946
Amyloidosis, FamilialIII1NCT04153149
PolyneuropathiesIII1NCT07223203

Everything on Vutrisiran

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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