Phuturdex › Diseases › Precancerous Conditions
Drugs in development · updated 30 October 2026
Precancerous Conditions: drugs in development
As of 30 October 2026 there are 4 active clinical trials (recruiting or ongoing, phases I–III) on 12 drugs for precancerous Conditions. 0 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| BusulfanBusulphan, Busulfex® | II | 3 | NCT06001385 |
| CyclophosphamideCyclophosphamid, Cytoxan | II | 3 | NCT06001385 |
| FludarabineFludara, FLUDARABIN | II | 3 | NCT06001385 |
| MelphalanEvomela®, Hepzato® | II | 3 | NCT06001385 |
| Mycophenolate MofetilMycophenolate, Cellcept | II | 3 | NCT06001385 |
| TacrolimusEnvarsus XR, Prograf® | II | 3 | NCT06001385 |
| MesnaUromitexan, Mesnex® | II | 2 | NCT06001385 |
| CyclosporineCyclosporine A, Cyclosporin Capsules | II | 1 | NCT00544115 |
| EtoposideAvopef®, Etopophos Preservative Free® | II | 1 | NCT00544115 |
| MethotrexateJylamvo®, Reditrex® | II | 1 | NCT00544115 |
| NivolumabOpdivo, ONO-4538 | II | 1 | NCT03347838 |
| SirolimusRapamycin, Scomara® | II | 1 | NCT00544115 |
Sorted by most advanced phase and number of active trials.
All 12 drugs, with the details
In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.
Open in Phuturdex →Specific forms
- Smoldering Multiple Myeloma 24 drugs
- Multiple myeloma 272 drugs
- Actinic keratosis 8 drugs
- Oral mucosa leukoplakia 3 drugs
- Barrett's esophagus 5 drugs
- Uterine Cervical Dysplasia 4 drugs
- Esophagus adenocarcinoma 82 drugs
- Preleukemia 10 drugs
- Monoclonal gammopathy of uncertain significance 3 drugs
- Mouth Neoplasms 49 drugs
- Papillomavirus infections 16 drugs
- Diffuse large B-cell lymphoma 177 drugs
Broader categories
- Neoplasm 671 drugs
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive 68 drugs
- Myeloid leukemia 26 drugs
- Myeloproliferative disorders 91 drugs
- Bone marrow disease 14 drugs
- Hematologic Diseases 57 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: NLM MeSH; NLM MeSH term: D011230 “Precancerous Conditions”.