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Drugs in development · updated 30 October 2026

Amivantamab: clinical trials and development status

Other names and codes: Rybrevant

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 9 December 2021

As of 30 October 2026 Amivantamab is in 41 active clinical trials (recruiting or ongoing, phases I–III) for 11 diseases. The most advanced phase is III.

41Active trials
IIIMost advanced phase
11Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Amivantamab and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Non-small-cell lung carcinomaIII22NCT04538664
Colorectal neoplasmIII4NCT06750094
Head and neck squamous cell carcinomaIII2NCT07276399
Lung neoplasmII2NCT06784791
Adenoid cystic carcinomaII1NCT05074940
Head and neck neoplasmsII1NCT07062354
MetastasisII1NCT05117931
NeoplasmII1NCT03767075
Salivary gland neoplasmII1NCT05074940
CarcinomaI1NCT07798921
GlioblastomaI1NCT06632236

Everything on Amivantamab

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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