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Drugs in development · updated 30 October 2026

Avapritinib: clinical trials and development status

Other names and codes: Ayvakit

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 24 September 2020

As of 30 October 2026 Avapritinib is in 9 active clinical trials (recruiting or ongoing, phases I–III) for 7 diseases. The most advanced phase is II.

9Active trials
IIMost advanced phase
7Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Avapritinib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Acute myeloid leukemiaII4NCT06783790
MetastasisII2NCT04116541
Colorectal neoplasmII1NCT04771520
Lung neoplasmII1NCT04771520
MelanomaII1NCT04771520
SarcomaII1NCT04771520
Systemic mastocytosisII1NCT03731260

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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