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Drugs in development · updated 30 October 2026

Daratumumab: clinical trials and development status

Other names and codes: Darzalex

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 20 May 2016

As of 30 October 2026 Daratumumab is in 175 active clinical trials (recruiting or ongoing, phases I–III) for 44 diseases. The most advanced phase is III.

175Active trials
IIIMost advanced phase
44Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Daratumumab and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 44 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Multiple myelomaIII120NCT07903272
Immunoglobulin Light-chain AmyloidosisIII9NCT07901725
NeoplasmIII9NCT07728188
Precursor T-cell lymphoblastic leukemiaII–III6NCT07072585
Plasma cell neoplasmIII5NCT07649525
Smoldering Multiple MyelomaIII5NCT07393282
AmyloidosisIII4NCT07901725
Residual neoplasmIII4NCT07740486
LymphomaII–III3NCT07072585
Plasma cell leukemiaIII3NCT07649525
Anti-N-Methyl-D-Aspartate Receptor EncephalitisIII1NCT06867991
Autoimmune disease of the nervous systemIII1NCT06867991
Frailty syndromeIII1NCT07649525
Neuromyelitis opticaII–III1NCT05403138
Autoimmune thrombocytopenic purpuraII4NCT07297563
Non-Hodgkin lymphomaII3NCT05907759
ParaproteinemiaII3NCT06889948
Acute myeloid leukemiaI–II2NCT04068597
Hematologic neoplasmI–II2NCT04068597
Plasmablastic lymphomaII2NCT04915248
Antiphospholipid syndromeI–II1NCT05671757
Aplastic anemiaI–II1NCT07287228
Autoimmune diseaseI–II1NCT05671757
Blood protein diseaseI–II1NCT05581875
Chromosome 17 deletionII1NCT04124497
Chronic lymphocytic leukemiaII1NCT03734198
Corneal diseaseI–II1NCT05581875
GlioblastomaI–II1NCT04922723
GlomerulonephritisII1NCT06889948
Hematologic DiseasesI–II1NCT05581875

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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