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Drugs in development · updated 30 October 2026

Ibuprofen: clinical trials and development status

Other names and codes: Advil, Caldolor, Children'S Elixsure, Midol Liquid Gels

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 28 July 2004

As of 30 October 2026 Ibuprofen is in 17 active clinical trials (recruiting or ongoing, phases I–III) for 17 diseases. The most advanced phase is III.

17Active trials
IIIMost advanced phase
17Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Ibuprofen and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Acute painIII1NCT07225634
Cancer painIII1NCT07682558
Knee InjuriesIII1NCT07145645
OsteoarthritisIII1NCT05318521
PainIII1NCT07006675
Sprains and strainsIII1NCT07145645
Tibial FracturesIII1NCT07006675
Patent ductus arteriosusII2NCT05340582
AgnosiaII1NCT07487246
Bipolar disorderI–II1NCT06088732
Chronic granulomatous diseaseII1NCT03055247
Dilatation, PathologicII1NCT07487246
Kidney neoplasmII1NCT05842044
Stomach neoplasmII1NCT07768514
Dental pulp necrosisEarly I1NCT07603934
Facial painEarly I1NCT04059172
Periapical periodontitisEarly I1NCT07603934

Everything on Ibuprofen

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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