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Drugs in development · updated 30 October 2026

Indocyanine Green: clinical trials and development status

Other names and codes: IC-Green, Zyogreen, Spy Agent Green Kit

NLM verified identityApproved in the US (FDA)

As of 30 October 2026 Indocyanine Green is in 22 active clinical trials (recruiting or ongoing, phases I–III) for 19 diseases. The most advanced phase is III.

22Active trials
IIIMost advanced phase
19Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Indocyanine Green and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
CarcinosarcomaIII1NCT05646316
NeoplasmII3NCT07149207
Biliary atresiaI–II2NCT07513038
Head and neck neoplasmsII2NCT07149207
Lung neoplasmI–II2NCT03953144
Non-small-cell lung carcinomaI–II2NCT03953144
SarcomaII2NCT07650656
Stomach neoplasmII2NCT05618821
Breast cancer lymphedemaII1NCT06327490
Breast neoplasmII1NCT06327490
Esophageal neoplasmI–II1NCT07108855
Head and neck squamous cell carcinomaII1NCT07149207
Margins of ExcisionII1NCT07149207
Mouth NeoplasmsII1NCT07518485
Brain NeoplasmsI2NCT07254845
Nervous system neoplasmI1NCT05746104
Rheumatoid arthritisI1NCT05197530
CholestasisEarly I1NCT07250854
LymphedemaEarly I1NCT07613931

Everything on Indocyanine Green

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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