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Drugs in development · updated 11 November 2026

Pegylated Liposomal Doxorubicin Hydrochloride: clinical trials and development status

Other names and codes: Liposomal Doxorubicin, DOXIL

NLM verified identityNot approved in the USNo EMA authorisationEstimated US launch Jan 2028 – Nov 2028 (Phuturdex estimate)

As of 11 November 2026 Pegylated Liposomal Doxorubicin Hydrochloride is in 34 active clinical trials (recruiting or ongoing, phases I–III) for 34 diseases. The most advanced phase is III.

Authorisation

Sources: EMA, AIFA register (open data), FDA. For Germany only the EU centralised authorisation is shown: the national BfArM register is not one of our sources.

Where Pegylated Liposomal Doxorubicin Hydrochloride trials are recruiting

Map of sites in Europe with recruitment status, every trial and an email when something changes. Full access free until 31 March 2027, no card needed.

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34Active trials
IIIMost advanced phase
34Diseases studied

What it is

Single use of pegylated liposomal doxorubicin has been reported to be safe and effective with varying treatment in patients with advanced hepatocellular carcinoma.

Source: NLM MeSH

Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 34 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Breast neoplasmIII5NCT04895358
Fallopian tube neoplasmIII5NCT05281471
Ovarian neoplasmIII5NCT05281471
Acquired Immunodeficiency SyndromeIII2NCT05411237
Kaposi's sarcomaIII2NCT05411237
MetastasisIII2NCT04895358
AIDS-related Kaposi sarcomaIII1NCT05411237
VacciniaIII1NCT05281471
SarcomaII4NCT06849986
LiposarcomaII3NCT06849986
Triple-negative breast neoplasmII3NCT06434064
Histiocytoma, Malignant FibrousII2NCT07817095
Hodgkin lymphomaII2NCT03618550
LeiomyosarcomaII2NCT06849986
Multi-centric Castleman's DiseaseII2NCT00092222
NeoplasmII2NCT00092222
Adenoviridae infectionsI–II1NCT05271318
CardiotoxicityII1NCT07654426
Desmoplastic small-round-cell tumorII1NCT06849986
Diffuse large B-cell lymphomaII1NCT07654426
FibrosarcomaII1NCT06849986
GlioblastomaII1NCT05864534
GliosarcomaII1NCT05864534
HemangiosarcomaII1NCT06849986
HIV infectionII1NCT00092222
LymphomaII1NCT07654426
Lymphoproliferative disordersII1NCT00092222
NeurofibrosarcomaII1NCT06849986
Ewing sarcomaI2NCT07194044
Dermatofibrosarcoma protuberansI1NCT05711615

Sites in Europe

100 sites of the active trials in 15 European countries, 4 recruiting.

Sites declared by the sponsors on ClinicalTrials.gov; region worked out by Phuturdex from the geographic point. The list of sites with city and recruitment status is in the app. See the sites →

Everything on Pegylated Liposomal Doxorubicin Hydrochloride

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 11 November 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, refers to the United States and is a Phuturdex calculation described on the Method page, not official data: the drug may already be marketed in other countries.

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