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Drugs in development · updated 30 October 2026

Penpulimab: clinical trials and development status

Other names and codes: AK105

NLM verified identityApproved in the US (FDA)

As of 30 October 2026 Penpulimab is in 29 active clinical trials (recruiting or ongoing, phases I–III) for 18 diseases. The most advanced phase is III.

29Active trials
IIIMost advanced phase
18Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Penpulimab and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Nasopharyngeal CarcinomaIII3NCT04974398
Hepatocellular carcinomaIII2NCT05862337
Head and neck squamous cell carcinomaII4NCT06081673
SarcomaII2NCT07612098
CarcinomaII1NCT05494060
Diffuse large B-cell lymphomaII1NCT06516978
Digestive System DiseasesII1NCT05494060
Esophageal neoplasmII1NCT06586242
Gastrointestinal diseaseII1NCT05494060
Gastrointestinal neoplasmII1NCT05494060
Head and neck neoplasmsII1NCT05260671
MelanomaII1NCT06500091
MetastasisII1NCT05260671
Nasopharyngeal neoplasmII1NCT05807880
Rectal neoplasmII1NCT05576480
Stomach neoplasmII1NCT05494060
Uterine cervix neoplasmII1NCT05137171
Colorectal neoplasmEarly I1NCT06853769

Everything on Penpulimab

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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