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Drugs in development · updated 30 October 2026

PF-08046054: clinical trials and development status

Development codeNot approved in the USNo EMA authorisationEstimated launch May 2029 – Mar 2030 (Phuturdex estimate)

As of 30 October 2026 PF-08046054 is in 3 active clinical trials (recruiting or ongoing, phases I–III) for 7 diseases. The most advanced phase is III.

3Active trials
IIIMost advanced phase
7Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow PF-08046054 and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Non-small-cell lung carcinomaIII3NCT07144280
Endometrial neoplasmI1NCT05208762
Esophageal squamous cell carcinomaI1NCT05208762
Head and neck squamous cell carcinomaI1NCT05208762
Hepatocellular carcinomaI1NCT05208762
Stomach neoplasmI1NCT05208762
Triple-negative breast neoplasmI1NCT05208762

Everything on PF-08046054

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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