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Drugs in development · updated 30 October 2026

Pyridostigmine: clinical trials and development status

Other names and codes: Regonol, Mestinon

NLM verified identityApproved in the US (FDA)

As of 30 October 2026 Pyridostigmine is in 6 active clinical trials (recruiting or ongoing, phases I–III) for 8 diseases. The most advanced phase is II–III.

6Active trials
II–IIIMost advanced phase
8Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Pyridostigmine and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Postural orthostatic tachycardia syndromeII2NCT00409435
Cognitive dysfunctionII1NCT06366724
ConstipationII1NCT05603715
Myalgic encephalomyelitis/chronic fatigue syndromeII1NCT06366724
Orthostatic hypotensionII1NCT01370512
Orthostatic intoleranceII1NCT06366724
Parkinson's diseaseII1NCT05603715
Post-Acute COVID-19 SyndromeII1NCT06366724

Everything on Pyridostigmine

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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