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Drugs in development · updated 5 November 2026

Acromegaly: drugs in development

Rare diseasePrevalence 1-9 / 100 000 according to Orphanet · ORPHA:963

What it is

A rare acquired endocrine disease related to excessive production of growth hormone (GH) and characterized by progressive somatic disfigurement (mainly involving the face and extremities) and systemic manifestations.

Source: Orphanet, “Acromegaly” (ORPHA:963), www.orpha.net · licence CC BY 4.0 · Orphadata data of 23 June 2026.

As of 5 November 2026 there are 4 active clinical trials (recruiting or ongoing, phases I–III) on 3 drugs for acromegaly. 3 are experimental, that is not yet approved in the United States.

4Active trials
3Experimental drugs
1Experimental, in phase III

Summary updated every week · data as of 5 November 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
Debio 4126III1NCT06930625
MAR002II2NCT07641179
NTQ6179I1NCT07909837

Sorted by most advanced phase and number of active trials.

All 3 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 5 November 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D000172 “Acromegaly”. Prevalence: Orphanet.

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