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Drugs in development · updated 30 October 2026

Adagrasib: clinical trials and development status

Other names and codes: MRTX849, Krazati

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 5 January 2024

As of 30 October 2026 Adagrasib is in 20 active clinical trials (recruiting or ongoing, phases I–III) for 11 diseases. The most advanced phase is III.

20Active trials
IIIMost advanced phase
11Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Adagrasib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Non-small-cell lung carcinomaIII12NCT06875310
Colorectal neoplasmIII7NCT04793958
Lung neoplasmIII5NCT06497556
MetastasisIII4NCT04685135
Colonic neoplasmIII3NCT04793958
Rectal neoplasmIII1NCT04793958
NeoplasmI–II2NCT03785249
Brain NeoplasmsII1NCT03994796
Pancreatic neoplasmI–II1NCT03785249
Renal cell carcinomaI2NCT06026410
Kidney neoplasmI1NCT06026410

Everything on Adagrasib

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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