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Drugs in development · updated 30 October 2026

Diclofenac: clinical trials and development status

Other names and codes: Voltaren Topical Gel, Zueino, Pennsaid, Zorvolex, Dyloject

NLM verified identityApproved in the US (FDA)

As of 30 October 2026 Diclofenac is in 13 active clinical trials (recruiting or ongoing, phases I–III) for 19 diseases. The most advanced phase is III.

13Active trials
IIIMost advanced phase
19Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Diclofenac and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
PainII–III2NCT07853664
Common bile duct diseaseII–III1NCT03595150
Dental pulp diseaseII–III1NCT06207253
Facial InjuriesII–III1NCT07853664
Knee InjuriesIII1NCT07145645
PancreatitisII–III1NCT03595150
Periapical periodontitisII–III1NCT06207253
Sprains and strainsIII1NCT07145645
Acute abdomenI–II1NCT06982755
Lower back painI–II1NCT06829030
Lung neoplasmII1NCT06731270
Non-small-cell lung carcinomaII1NCT06731270
Postoperative painI–II1NCT06158620
UrolithiasisI–II1NCT06158620
Fractures, BoneI1NCT05883241
OsteoarthritisI1NCT05254574
AlcoholismEarly I1NCT06029296
Chronic painEarly I1NCT07837284
Knee osteoarthritisEarly I1NCT07837284

Everything on Diclofenac

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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