PhuturdexDrug Pipeline Intelligence

Phuturdex › Drugs › Entrectinib

Drugs in development · updated 30 October 2026

Entrectinib: clinical trials and development status

Other names and codes: Rozlytrek

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 31 July 2020

As of 30 October 2026 Entrectinib is in 17 active clinical trials (recruiting or ongoing, phases I–III) for 27 diseases. The most advanced phase is III.

17Active trials
IIIMost advanced phase
27Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Entrectinib and get an email at every change or safety alert.

Sign in free →

Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Non-small-cell lung carcinomaIII5NCT04603807
Brain NeoplasmsII–III4NCT05770544
NeoplasmIII4NCT05862285
GliomaII–III3NCT05770544
Hematologic neoplasmII–III3NCT05722886
Lymphoproliferative disordersII–III2NCT05722886
MelanomaII–III2NCT05770544
Central nervous system neoplasmII2NCT06528691
MetastasisII2NCT03994796
Papillary thyroid cancerII2NCT02568267
Salivary gland neoplasmII2NCT02568267
SarcomaII2NCT02568267
Anaplastic large-cell lymphomaII1NCT02568267
Breast neoplasmII1NCT02568267
CholangiocarcinomaII1NCT02568267
Colorectal neoplasmII1NCT02568267
Ewing sarcomaI–II1NCT02650401
Head and neck neoplasmsII1NCT02568267
MedulloblastomaI–II1NCT02650401
Mesoblastic nephromaI–II1NCT02650401
NeuroblastomaI–II1NCT02650401
Neuroendocrine tumorII1NCT02568267
Ovarian neoplasmII1NCT02568267
Pancreatic neoplasmII1NCT02568267
Renal cell carcinomaII1NCT02568267
Wilms TumorI–II1NCT02650401
Acute myeloid leukemiaI1NCT05396859

Everything on Entrectinib

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

Open in Phuturdex →

Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

ItalianoFrançaisDeutsch