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Drugs in development · updated 30 October 2026

Retlirafusp alfa: clinical trials and development status

Other names and codes: SHR-1701

NLM verified identityNot approved in the USNo EMA authorisationEstimated launch Feb 2030 – Dec 2030 (Phuturdex estimate)

As of 30 October 2026 Retlirafusp alfa is in 44 active clinical trials (recruiting or ongoing, phases I–III) for 11 diseases. The most advanced phase is III.

44Active trials
IIIMost advanced phase
11Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Retlirafusp alfa and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Stomach neoplasmII7NCT07904442
Esophageal squamous cell carcinomaII3NCT07709533
Non-small-cell lung carcinomaII3NCT07619911
Pancreatic neoplasmII3NCT07814859
Colorectal neoplasmII2NCT07728019
CholangiocarcinomaII1NCT07847710
Esophageal neoplasmII1NCT07770672
Hepatocellular carcinomaII1NCT07749859
MelanomaII1NCT07517653
Ovarian neoplasmII1NCT07355010
Triple-negative breast neoplasmII1NCT07752550

Everything on Retlirafusp alfa

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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