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Drugs in development · updated 30 October 2026

Sorafenib: clinical trials and development status

Other names and codes: Nexavar

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 19 July 2006

As of 30 October 2026 Sorafenib is in 37 active clinical trials (recruiting or ongoing, phases I–III) for 25 diseases. The most advanced phase is III.

37Active trials
IIIMost advanced phase
25Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Sorafenib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Hepatocellular carcinomaIII9NCT03298451
Acute myeloid leukemiaIII8NCT07463651
NeoplasmIII3NCT03755791
Fibrolamellar hepatocellular carcinomaIII2NCT03533582
HepatoblastomaIII2NCT03533582
CarcinomaIII1NCT03755791
Liver neoplasmIII1NCT07836530
Residual neoplasmII–III1NCT07264010
MetastasisII2NCT02029001
Myelodysplastic SyndromesII2NCT03164057
NeuroblastomaII2NCT02559778
Breast neoplasmII1NCT05594095
Gastrointestinal stromal tumorII1NCT00265798
Head and neck squamous cell carcinomaII1NCT00494182
Leukemia, Myelogenous, Chronic, BCR-ABL PositiveII1NCT06532084
Myeloproliferative disordersII1NCT06532084
OsteosarcomaII1NCT07787429
Renal cell carcinomaII1NCT06690697
RhabdomyosarcomaII1NCT01871766
Thyroid gland diseaseII1NCT01141309
Thyroid Hurthle cell carcinomaII1NCT02143726
Thyroid neoplasmII1NCT01141309
Type-1 diabetesII1NCT06227221
MelanomaI1NCT01303341
Precursor lymphoblastic lymphoma/leukemiaI1NCT03132454

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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