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Drugs in development · updated 30 October 2026

Tunlametinib: clinical trials and development status

Other names and codes: HL-085

FDA substance registryNot approved in the USNo EMA authorisationEstimated launch Feb 2028 – Dec 2028 (Phuturdex estimate)

As of 30 October 2026 Tunlametinib is in 8 active clinical trials (recruiting or ongoing, phases I–III) for 6 diseases. The most advanced phase is III.

8Active trials
IIIMost advanced phase
6Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Tunlametinib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
MelanomaIII2NCT06008106
Lung neoplasmII1NCT07463677
Neurofibromatosis 1II1NCT05331105
Non-small-cell lung carcinomaII1NCT07463677
Plexiform neurofibromaII1NCT05331105
Thyroid neoplasmII1NCT06970353

Everything on Tunlametinib

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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