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Drugs in development · updated 30 October 2026

Encorafenib: clinical trials and development status

Other names and codes: Braftovi

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 19 September 2018

As of 30 October 2026 Encorafenib is in 35 active clinical trials (recruiting or ongoing, phases I–III) for 20 diseases. The most advanced phase is III.

35Active trials
IIIMost advanced phase
20Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Encorafenib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
MelanomaIII14NCT04657991
Colorectal neoplasmIII11NCT04607421
Colonic neoplasmIII8NCT03803553
Rectal neoplasmIII4NCT04607421
NeoplasmIII2NCT04607421
Skin neoplasmIII2NCT04657991
Biliary tract neoplasmIII1NCT05615818
Colonic diseaseIII1NCT04607421
Digestive System DiseasesIII1NCT04607421
Digestive system neoplasmIII1NCT04607421
Gastrointestinal diseaseIII1NCT04607421
Gastrointestinal neoplasmIII1NCT04607421
Intestinal diseaseIII1NCT04607421
Intestinal neoplasmIII1NCT04607421
Rectal diseaseIII1NCT04607421
Brain NeoplasmsII6NCT04511013
Non-small-cell lung carcinomaII2NCT04526782
Hairy cell leukemiaII1NCT04324112
Lung neoplasmII1NCT05195632
Thyroid neoplasmII1NCT04061980

Everything on Encorafenib

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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