Phuturdex › Diseases › Intestinal neoplasm
Drugs in development · updated 30 October 2026
Intestinal neoplasm: drugs in development
As of 30 October 2026 there are 10 active clinical trials (recruiting or ongoing, phases I–III) on 16 drugs for intestinal neoplasm. 5 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Experimental drugs
Not yet approved by the US FDA for any indication.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| PF-08634404 | III | 1 | NCT07222800 |
| ElironrasibRMC-6291 | I–II | 2 | NCT06128551 |
| RMC-6236 | I–II | 1 | NCT05379985 |
| SL-28 | I–II | 1 | NCT07341737 |
| KFA115 | I | 1 | NCT05544929 |
Sorted by most advanced phase and number of active trials.
Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| Bevacizumabavastin, MVASI | III | 3 | NCT07222800 |
| IrinotecanOnivyde, CPT-11 | III | 2 | NCT04607421 |
| CapecitabineXeloda, Capectitabine Tablets | III | 1 | NCT04607421 |
| CetuximabErbitux | III | 1 | NCT04607421 |
| EncorafenibBraftovi® | III | 1 | NCT04607421 |
| LeucovorinFolinic acid, l-leucovorin | III | 1 | NCT04607421 |
| OxaliplatinOxaliplatine, Oxaliplain | III | 1 | NCT04607421 |
| ArtesunateArtesunate Amivas®, Garsun® | II | 1 | NCT07095309 |
| DaraxonrasibRasonque® | I–II | 1 | NCT06128551 |
| RepotrectinibAugtyro® | I–II | 1 | NCT03093116 |
| PembrolizumabKEYTRUDA, MK-3475 | I | 1 | NCT05544929 |
Sorted by most advanced phase and number of active trials.
All 16 drugs, with the details
In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.
Open in Phuturdex →Specific forms
- Colorectal neoplasm 534 drugs
- Rectal neoplasm 131 drugs
- Non-small-cell lung carcinoma 726 drugs
- Colonic neoplasm 157 drugs
- Pancreatic neoplasm 395 drugs
- Stomach neoplasm 340 drugs
- Neoplasm 671 drugs
- Metastasis 493 drugs
- Ovarian neoplasm 411 drugs
- Breast neoplasm 593 drugs
- Endometrial neoplasm 298 drugs
- Head and neck squamous cell carcinoma 321 drugs
Broader categories
- Digestive System Diseases 36 drugs
- Gastrointestinal disease 22 drugs
- Intestinal disease 15 drugs
- Glandular and epithelial neoplasm 12 drugs
- Digestive system neoplasm 37 drugs
- Colonic disease 11 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D007414 “Intestinal Neoplasms”.