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Drugs in development · updated 30 October 2026

Repotrectinib: clinical trials and development status

Other names and codes: Augtyro

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 13 January 2025

As of 30 October 2026 Repotrectinib is in 6 active clinical trials (recruiting or ongoing, phases I–III) for 35 diseases. The most advanced phase is III.

6Active trials
IIIMost advanced phase
35Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Repotrectinib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 35 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Non-small-cell lung carcinomaIII4NCT06140836
MetastasisI–II2NCT04094610
SarcomaI–II2NCT04094610
AdenocarcinomaI–II1NCT03093116
Anaplastic large-cell lymphomaI–II1NCT04094610
Brain NeoplasmsII1NCT06315010
Bronchial neoplasmI–II1NCT03093116
CarcinomaI–II1NCT03093116
Carcinoma, BronchogenicI–II1NCT03093116
Colonic diseaseI–II1NCT03093116
Colonic neoplasmI–II1NCT03093116
Digestive system neoplasmI–II1NCT03093116
Endocrine gland neoplasmI–II1NCT03093116
Endocrine system diseaseI–II1NCT03093116
Gastrointestinal diseaseI–II1NCT03093116
Gastrointestinal neoplasmI–II1NCT03093116
Germ cell and embryonal neoplasmsI–II1NCT03093116
GlioblastomaI–II1NCT04094610
GliomaI–II1NCT04094610
Head and neck neoplasmsI–II1NCT03093116
Intestinal diseaseI–II1NCT03093116
Intestinal neoplasmI–II1NCT03093116
Lung diseaseI–II1NCT03093116
Lung neoplasmI–II1NCT03093116
LymphomaI–II1NCT04094610
NeoplasmI–II1NCT03093116
Neuroectodermal tumorI–II1NCT03093116
Neuroendocrine carcinomaI–II1NCT03093116
Neuroendocrine tumorI–II1NCT03093116
Respiratory diseaseI–II1NCT03093116

Everything on Repotrectinib

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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