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Drugs in development · updated 30 October 2026

Iopofosine I 131: clinical trials and development status

Other names and codes: CLR 131

FDA substance registryNot approved in the USNo EMA authorisationEstimated launch Mar 2033 – Jan 2034 (Phuturdex estimate)

As of 30 October 2026 Iopofosine I 131 is in 4 active clinical trials (recruiting or ongoing, phases I–III) for 23 diseases. The most advanced phase is III.

4Active trials
IIIMost advanced phase
23Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Iopofosine I 131 and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Waldenstrom MacroglobulinemiaIII1NCT07766421
GliomaI2NCT03478462
Breast neoplasmI1NCT07311993
Desmoplastic small-round-cell tumorI1NCT03478462
Diffuse Intrinsic Pontine GliomaI1NCT03478462
EpendymomaI1NCT03478462
Ewing sarcomaI1NCT03478462
GlioblastomaI1NCT03478462
GliosarcomaI1NCT03478462
Hodgkin lymphomaI1NCT03478462
LymphomaI1NCT03478462
MedulloblastomaI1NCT03478462
NeuroblastomaI1NCT03478462
Neuroepithelial neoplasmI1NCT03478462
Non-Hodgkin lymphomaI1NCT03478462
OsteosarcomaI1NCT03478462
Primitive neuroectodermal tumorI1NCT03478462
Rhabdoid tumorI1NCT03478462
RhabdomyosarcomaI1NCT03478462
SarcomaI1NCT03478462
Synovial sarcomaI1NCT03478462
Triple-negative breast neoplasmI1NCT07311993
Wilms TumorI1NCT03478462

Everything on Iopofosine I 131

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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