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Drugs in development · updated 30 October 2026

Sargramostim: clinical trials and development status

Other names and codes: rhuGM-CSF, leukine, Imreplys

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 21 August 2025

As of 30 October 2026 Sargramostim is in 25 active clinical trials (recruiting or ongoing, phases I–III) for 29 diseases. The most advanced phase is III.

25Active trials
IIIMost advanced phase
29Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Sargramostim and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
NeuroblastomaIII6NCT03126916
GanglioneuroblastomaIII3NCT03126916
MelanomaII–III3NCT02339571
Lung neoplasmII4NCT07169617
Triple-negative breast neoplasmII4NCT07078604
Non-small-cell lung carcinomaII3NCT05242965
NeoplasmII2NCT04300244
Alzheimer's diseaseII1NCT04902703
Breast lobular carcinomaI–II1NCT05269381
Breast neoplasmII1NCT03012100
CarcinosarcomaI–II1NCT05269381
Endometrial neoplasmI–II1NCT05269381
GlioblastomaII1NCT02455557
GliosarcomaII1NCT02455557
Head and neck squamous cell carcinomaI–II1NCT05269381
Hepatocellular carcinomaI–II1NCT05269381
Inflammatory breast cancerII1NCT03012100
Islet cell adenomaII1NCT06202066
Malignant mesotheliomaII1NCT04300244
Merkel cell carcinomaI–II1NCT05269381
MesotheliomaII1NCT04300244
MetastasisI–II1NCT05269381
Renal cell carcinomaI–II1NCT05269381
Stomach neoplasmII1NCT05771584
Transitional cell carcinomaI–II1NCT05269381
Unilateral breast neoplasmII1NCT03012100
Uterine cervix neoplasmI–II1NCT05269381
Multiple myelomaI1NCT02334865
Plasma cell leukemiaI1NCT02334865

Everything on Sargramostim

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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