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Drugs in development · updated 9 November 2026

Hemic and lymphatic diseases: drugs in development

What it is

Hematologic diseases and diseases of the lymphatic system collectively. Hemic diseases include disorders involving the formed elements (e.g., ERYTHROCYTE AGGREGATION, INTRAVASCULAR) and chemical components (e.g., BLOOD PROTEIN DISORDERS); lymphatic diseases include disorders relating to lymph, lymph nodes, and lymphocytes.

Source: NLM MeSH (U.S. National Library of Medicine), descriptor D006425, meshb.nlm.nih.gov · public domain · downloaded on 9 November 2026.

As of 9 November 2026 there are 3,502 active clinical trials (recruiting or ongoing, phases I–III) on 1,358 drugs for hemic and lymphatic diseases. 870 are experimental, that is not yet approved in the United States.

3,502Active trials
870Experimental drugs
149Experimental, in phase III

Summary updated every week · data as of 9 November 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
ChidamideTucidinostatIII44NCT06947967
OrelabrutinibICP-022II–III41NCT06378138
GolidocitinibII–III22NCT07339345
LisaftoclaxAPG-2575, LisafotoclaxII–III19NCT07597941
MezigdomideCC-92480III18NCT05519085
NemtabrutinibIII15NCT05947851
GolcadomideCC-99282III14NCT06356129
EtentamigABBV-383, TNB-383BII–III13NCT07095452
CevostamabIII12NCT07555938
OdronextamabOrdspono®II–III11NCT05991388
CM336III10NCT07910903
LinperlisibII–III10NCT06548347
OlverembatinibHQP1351III10NCT06423911
SurovatamigAZD0486III9NCT07911553
BomedemstatIMG-7289II–III8NCT07722611
CPX-351III8NCT03897127
GM-CSFGranulocyte-Macrophage Colony-Stimulating FactorIII7NCT04229979
MK-1045II–III7NCT07917754
TacabrutidegIII7NCT06973187
Zilovertamab vedotinII–III7NCT07917754
AZD0120III6NCT07735637
ICP-248II–III6NCT06378138
JNJ-79635322III6NCT07258511
NavitoclaxIII6NCT04468984
RocbrutinibIII6NCT07342478
AclarubicinII–III5NCT07651163
DZD8586III5NCT07139873
ElriterceptIII5NCT06499285
IanalumabVAY736III5NCT05653219
NavtemadlinKRT-232III5NCT06479135
PelabresibIII5NCT07357727
SR604III5NCT07876674
VindesineVindelsineII–III5NCT02405676
CM313 injectionIII4NCT07910903
EtavopivatIII4NCT06612268
IBI3003III4NCT07623798
MY008211AII–III4NCT06933914
NX-5948III4NCT07516093
RamantamigIII4NCT07903272
SCTB35III4NCT07562022

Sorted by most advanced phase and number of active trials. Showing 40 of 870 drugs.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
CyclophosphamideCyclophosphamid, CytoxanII–III436NCT04799275
VenetoclaxVentoclax, veneclaxII–III347NCT03984448
DexamethasoneDexametasone, dexamethsoneII–III325NCT07570173
RituximabRuxience, RituxanII–III313NCT07917754
FludarabineFludara, FLUDARABINII–III272NCT01949129
LenalidomideRevlimid, Lenalidomide Mylan®II–III246NCT07917754
AzacitidineAzacytidine, 5-azacytidineII–III210NCT04799275
CytarabineAra-C, Cytosine ArabinosideII–III196NCT07255872
PrednisoneCortancyl, PredinisoneII–III147NCT04799275
DaratumumabDarzalexII–III144NCT07887984
DoxorubicinAdriamycin, DoxorubincinII–III144NCT04799275
VincristineVincristin, Oncovin [vincristine]II–III137NCT04799275
ObinutuzumabGazyva®, Gazyvaro®II–III129NCT07724457
BortezomibVelcade, Bortezomib Hospira®II–III114NCT07887984
ZanubrutinibZaunbrutinib, BGB-3111III98NCT05976763

Sorted by most advanced phase and number of active trials. Showing 15 of 488 drugs.

All 1,358 drugs, with the details

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Specific forms

Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 9 November 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D006425 “Hemic and Lymphatic Diseases”.

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