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Drugs in development · updated 30 October 2026

Afatinib: clinical trials and development status

Other names and codes: Gilotrif

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 25 September 2013

As of 30 October 2026 Afatinib is in 24 active clinical trials (recruiting or ongoing, phases I–III) for 33 diseases. The most advanced phase is III.

24Active trials
IIIMost advanced phase
33Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Afatinib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 33 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Non-small-cell lung carcinomaIII5NCT06486142
Esophageal squamous cell carcinomaII–III1NCT07653451
LymphomaII3NCT02465060
Multiple myelomaII3NCT02465060
Colonic neoplasmII2NCT02465060
Colorectal neoplasmII2NCT02465060
Esophageal neoplasmII2NCT02465060
Head and neck squamous cell carcinomaI–II2NCT07010120
Hematologic neoplasmII2NCT02465060
Lung neoplasmII2NCT02465060
MetastasisI–II2NCT03785249
NeoplasmII2NCT02925234
Pancreatic neoplasmII2NCT02465060
Stomach neoplasmII2NCT02465060
Adenocarcinoma of the lungII1NCT05215548
Bladder neoplasmII1NCT02465060
Breast neoplasmII1NCT02465060
Endometrial neoplasmII1NCT02465060
Fanconi anemiaI–II1NCT06648096
Gallbladder neoplasmII1NCT04183712
GliomaII1NCT02465060
Hepatocellular carcinomaII1NCT02465060
MelanomaII1NCT02465060
Ovarian neoplasmII1NCT02465060
Prostatic NeoplasmsII1NCT02465060
Rectal neoplasmII1NCT02465060
Skin neoplasmII1NCT05070403
Squamous cell carcinomaII1NCT05070403
Thyroid neoplasmII1NCT02465060
Uterine cervix neoplasmII1NCT02465060

Everything on Afatinib

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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