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Drugs in development · updated 30 October 2026

Gotistobart: clinical trials and development status

Other names and codes: ONC-392

FDA substance registryNot approved in the USNo EMA authorisationEstimated launch Oct 2028 – Aug 2029 (Phuturdex estimate)

As of 30 October 2026 Gotistobart is in 4 active clinical trials (recruiting or ongoing, phases I–III) for 17 diseases. The most advanced phase is III.

4Active trials
IIIMost advanced phase
17Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Gotistobart and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Non-small-cell lung carcinomaIII2NCT05671510
Ovarian neoplasmII2NCT05446298
Adenoid cystic carcinomaI–II1NCT04140526
Breast neoplasmI–II1NCT04140526
Colorectal neoplasmI–II1NCT04140526
Esophageal neoplasmI–II1NCT04140526
Fallopian tube neoplasmII1NCT05446298
Lung small cell carcinomaI–II1NCT04140526
MelanomaI–II1NCT04140526
Pancreatic neoplasmI–II1NCT04140526
Prostatic NeoplasmsI–II1NCT04140526
Renal cell carcinomaI–II1NCT04140526
Salivary gland neoplasmI–II1NCT04140526
SarcomaI–II1NCT04140526
Stomach neoplasmI–II1NCT04140526
Transitional cell carcinomaI–II1NCT04140526
Uterine cervix neoplasmI–II1NCT04140526

Everything on Gotistobart

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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