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Drugs in development · updated 30 October 2026

Memantine: clinical trials and development status

Other names and codes: Namenda, Ebixa

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 15 May 2002

As of 30 October 2026 Memantine is in 30 active clinical trials (recruiting or ongoing, phases I–III) for 30 diseases. The most advanced phase is III.

30Active trials
IIIMost advanced phase
30Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Memantine and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Brain NeoplasmsIII6NCT04804644
Alzheimer's diseaseIII3NCT07251023
ConcussionII–III2NCT06914310
Hepatocellular carcinomaII–III2NCT06007846
Traumatic brain injuryII–III2NCT06914310
Amyotrophic lateral sclerosisII–III1NCT04302870
Cognition DisordersIII1NCT06275035
Excoriation disorderII–III1NCT05796752
FibrosisII–III1NCT06007846
Lung neoplasmIII1NCT04804644
Lung small cell carcinomaIII1NCT04804644
Peripheral Nervous System DiseasesII–III1NCT07504198
TrichotillomaniaII–III1NCT05796752
Cognitive dysfunctionII2NCT06727773
Breast neoplasmII1NCT06727773
EpilepsyI–II1NCT05664464
Fragile X syndromeII1NCT05418049
GlioblastomaI–II1NCT05664464
Obsessive-compulsive disorderII1NCT04539951
OsteoporosisII1NCT06041789
Postural orthostatic tachycardia syndromeI–II1NCT00262470
Prostatic NeoplasmsII1NCT07164794
Sinus tachycardiaI–II1NCT00262470
TachycardiaI–II1NCT00262470
DepressionI2NCT07139834
Major depressive disorderI2NCT07139834
Down syndromeI1NCT07531940
Intellectual disabilityI1NCT07531940
Psychotic disorderI1NCT04789915
Ischemic strokeEarly I1NCT02144584

Everything on Memantine

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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