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Drugs in development · updated 30 October 2026

Tarlatamab: clinical trials and development status

Other names and codes: AMG 757, Imdelltra

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 29 May 2026

As of 30 October 2026 Tarlatamab is in 35 active clinical trials (recruiting or ongoing, phases I–III) for 24 diseases. The most advanced phase is III.

35Active trials
IIIMost advanced phase
24Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Tarlatamab and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Lung small cell carcinomaIII17NCT07778316
Neuroendocrine carcinomaIII3NCT06937905
NeoplasmII5NCT07895056
GliomaI–II2NCT07243470
Non-small-cell lung carcinomaII2NCT07242547
AstrocytomaII1NCT06776250
Bladder neoplasmI–II1NCT06814496
Brain NeoplasmsII1NCT07402343
Central nervous system neoplasmI–II1NCT07243470
EsthesioneuroblastomaI–II1NCT06814496
GlioblastomaI–II1NCT06814496
Medullary carcinomaI–II1NCT06814496
MelanomaI–II1NCT06814496
Merkel cell carcinomaI–II1NCT06814496
MetastasisII1NCT07016230
Neuroendocrine tumorII1NCT06502977
Prostatic NeoplasmsII1NCT07111507
Respiratory tract neoplasmII1NCT07242547
Sinonasal undifferentiated carcinomaI–II1NCT06814496
Testicular NeoplasmsI–II1NCT06814496
Thoracic NeoplasmsII1NCT07242547
Uterine cervix neoplasmI–II1NCT06814496
Bites and stingsI2NCT05361395
Lung neoplasmI1NCT05361395

Everything on Tarlatamab

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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